“We weren’t surprised that there were changes,” he said. “But the magnitude was rather astounding. In a disease population, there aren’t five drugs in combination that would cause this aggregate of an improvement….” The researchers looked at measures of quality of life and discovered that the calorie-restricted group reported better sleep, increased energy and improved mood…. One question the study could not answer was whether caloric restriction could extend life span in humans the way that it can in other animals… But ultimately, caloric restriction did have a beneficial impact on a wide range of risk factors for diabetes and heart disease, two conditions that cause death and disability for millions of Americans, especially as they get older.
Asked about the study, the chairman of the nutrition department at Harvard’s School of Public Health questioned whether caloric restriction would be practical for most people, given that “we are living in an obesogenic environment with an abundance of energy-dense, nutrient-poor foods that are cheap, accessible and heavily marketed.”